Open Access<p>Zirconium Oxide Thin Films Obtained by Atomic Layer Deposition Technology Abolish the Anti-Osteogenic Effect Resulting from miR-21 Inhibition in the Pre-Osteoblastic MC3T3 Cell Line</p>
Author(s) -
Aleksandra Seweryn,
Ariadna Pielok,
K. Ławniczak-Jabłońska,
R. Pietruszka,
Klaudia Marcinkowska,
Mateusz Sikora,
B.S. Witkowski,
M. Godlewski,
Krzysztof Marycz,
Agnieszka Śmieszek
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s237898
Subject(s) - osteopontin , osteocalcin , biocompatibility , cell culture , materials science , alkaline phosphatase , osteoblast , cell growth , microbiology and biotechnology , cell , chemistry , in vitro , biology , biochemistry , immunology , genetics , metallurgy , enzyme
The development of the field of biomaterials engineering is rapid. Various bioactive coatings are created to improve the biocompatibility of substrates used for bone regeneration, which includes formulation of thin zirconia coatings with pro-osteogenic properties. The aim of this study was to assess the biological properties of ZrO 2 thin films grown by Atomic Layer Deposition (ALD) technology (ZrO 2 ALD ).