Open Access<p>Virus-Like Particles Presenting the FGF-2 Protein or Identified Antigenic Peptides Promoted Antitumor Immune Responses in Mice</p>
Author(s) -
Congyan Shu,
Pengyan Sun,
Hanghang Xie,
Weiwei Huang,
Jialong Qi,
Yanbing Ma
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s237182
Subject(s) - immune system , cytotoxic t cell , antigen , cancer research , biology , epitope , immunology , microbiology and biotechnology , in vitro , biochemistry
Fibroblast growth factor (FGF)-2 is overexpressed in various tumor tissues. It affects tumor cell proliferation, invasion and survival, promotes tumor angiogenesis and is tightly involved in the development of systemic and local immunosuppressive tumor mechanisms.