Open Access<p>Anticancer Effects of Zinc Oxide Nanoparticles Through Altering the Methylation Status of Histone on Bladder Cancer Cells</p>
Author(s) -
Tianke Zhang,
Eugenie Du,
Yan Liu,
Jun Cheng,
Zhihong Zhang,
Yong Xu,
Shiyong Qi,
Yue Chen
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s228839
Subject(s) - apoptosis , epigenetics , cell cycle , histone , chemistry , cancer research , ezh2 , dna damage , chromatin , microbiology and biotechnology , biology , biochemistry , dna , gene
Zinc oxide nanoparticles (nZnO) have been widely used in the medicine field. Numerous mechanistic studies for nZnO's anticancer effects are merely performed under high concentration exposure. However, possible anticancer mechanisms of epigenetic dysregulation induced by low doses of nZnO are unclear.