Open Access<p>Pre-Treatment with Zirconia Nanoparticles Reduces Inflammation Induced by the Pathogenic H5N1 Influenza Virus</p>
Author(s) -
Caiyun Huo,
Jin Xiao,
Kai Xiao,
Shumei Zou,
Ming Wang,
Qi Peng,
Tianlong Liu,
Yanxin Hu
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s221667
Subject(s) - virus , influenza a virus , influenza a virus subtype h5n1 , in vivo , innate immune system , inflammation , virology , viral replication , antiviral drug , immune system , immunology , biology , microbiology and biotechnology
New approaches are urgently needed to fight influenza viral infection. Previous research has shown that zirconia nanoparticles can be used as anticancer materials, but their antiviral activity has not been reported. Here, we investigated the antiviral effect of zirconia (ZrO 2 ) nanoparticles (NPs) against a highly pathogenic avian influenza virus.