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Owing to its combined effects, the co-delivery of different therapeutics is a promising option for the treatment of cancer. In the present study, tumor-targeting poly(ethylene glycol)-poly(lactic acid) (PEG-PLA) nanoparticles were developed for the transportation of two molecules, namely chemotherapeutic drug 5-fluorouracil (5Fu) and radionuclide iodine-131 ( 131 I), in a single platform.

international journal of nanomedicine

&lt;p&gt;Combined Therapeutic Effects of &lt;sup&gt;131&lt;/sup&gt;I-Labeled and 5Fu-Loaded Multifunctional Nanoparticles in Colorectal Cancer&lt;/p&gt;