Open Access<p>Glucose-coated Berberine Nanodrug for Glioma Therapy through Mitochondrial Pathway</p>
Author(s) -
Shubin Wang,
Juan An,
Wei Dong,
Xin Wang,
Jian-qiu Sheng,
Yan Jia,
Yuqi He,
Xianzong Ma,
Jiheng Wang,
Dedong Yu,
Xiuqin Jia,
Bingyu Wang,
Wenbo Yu,
Kejia Liu,
Yuanyuan Zhao,
Yun Wu,
Wei Zhu,
Yuanming Pan
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s213079
Subject(s) - glioma , berberine , viability assay , chemistry , blot , flow cytometry , microbiology and biotechnology , apoptosis , mtt assay , confocal microscopy , immunofluorescence , biochemistry , cancer research , antibody , biology , immunology , gene
Glioma is the primary malignant brain tumor with poor prognosis. Berberine (BBR) was the potential drug for anti-tumor in glioma cells. Based on its limitation of poor aqueous solubility and instability, little information of BBR nanoparticles is reported in glioma.