Open Access<p>Nano Encapsulated Curcumin: And Its Potential for Biomedical Applications</p>
Author(s) -
Yan Chen,
Yao Lu,
Robert J. Lee,
Guangya Xiang
Publication year - 2020
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s210320
Subject(s) - curcumin , bioavailability , biocompatibility , polyphenol , pharmacology , nanotechnology , chemistry , materials science , medicine , antioxidant , biochemistry , organic chemistry
Curcumin, a yellow-colored polyphenol extracted from the rhizome of turmeric root, is commonly used as a spice and nutritional supplement. It exhibits many pharmacological activities such as anti-inflammatory, anti-bacterial, anti-cancer, anti-Alzheimer, and anti-fungal. However, the therapeutic application of curcumin is limited by its extremely low solubility in aqueous buffer, instability in body fluids, and rapid metabolism. Nano delivery system has shown excellent potential to improve the solubility, biocompatibility and therapeutic effect of curcumin. In this review, we focus on the recent development of nano encapsulated curcumin and its potential for biomedical applications.