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Degradation of the extracellular matrix (ECM) changes the physicochemical properties and dysregulates ECM-cell interactions, leading to several pathological conditions, such as invasive cancer. Carbon nanofilm, as a biocompatible and easy to functionalize material, could be used to mimic ECM structures, changing cancer cell behavior to perform like normal cells.

international journal of nanomedicine

&lt;p&gt;Mechano-signalling, induced by fullerene C&lt;sub&gt;60&lt;/sub&gt; nanofilms, arrests the cell cycle in the G2/M phase and decreases proliferation of liver cancer cells&lt;/p&gt;