Open Access<p>DIBc, a nanochelating-based nano metal-organic framework, shows anti-diabetic effects in high-fat diet and streptozotocin-induced diabetic rats</p>
Author(s) -
Saideh Fakharzadeh,
Somayeh Kalanaky,
Maryam Hafizi,
Mohammad Hassan Nazaran,
Homeira Zardooz
Publication year - 2019
Publication title -
international journal of nanomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.245
H-Index - 128
eISSN - 1178-2013
pISSN - 1176-9114
DOI - 10.2147/ijn.s196050
Subject(s) - metformin , streptozotocin , medicine , triglyceride , diabetes mellitus , endocrinology , malondialdehyde , insulin resistance , high density lipoprotein , cholesterol , oxidative stress
Despite daily increase in diabetic patients in the world, currently approved medications for this disease, at best, only reduce its progression speed. Using novel technologies is a solution for synthetizing more efficient medicines. In the present study, we evaluated anti-diabetic effects of DIBc, a nano metal-organic framework, which is synthetized based on nanochelating technology.