Open AccessIntegrative Multi-Omics Analysis of Identified SKA3 as a Candidate Oncogene Correlates with Poor Prognosis and Immune Infiltration in Lung Adenocarcinoma
Author(s) -
Yuansheng Lin,
Jianzhong An,
Xingli Zhuo,
Yingzhuo Qiu,
Wei Xie,
Wei Yao,
Dan Yin,
Linpeng Wu,
Dian Lei,
Chenghui Li,
Xie Yuanguang,
Ahu Hu,
Shengjun Li
Publication year - 2022
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s359987
Subject(s) - immune system , adenocarcinoma , cd8 , oncogene , cancer research , mitosis , cell cycle , biology , infiltration (hvac) , medicine , immunology , cell , cancer , microbiology and biotechnology , genetics , physics , thermodynamics
Spindle and kinetochore-associated complex subunit 3 (SKA3) plays important roles in promoting the migration and the invasion of various human cancer cells. There are a few studies on SKA3 in lung adenocarcinoma (LUAD), but the in-depth analysis of the expression of SKA3 and the correlated possible immune mechanism of SKA3 in LUAD are not clear.