Open AccessDiagnosis of Low Bone Mass Density: Serological versus Radiological Methods
Author(s) -
Osama A. Shaikhomar,
Abdelghnay H Abdelghnay,
Haitham MH Qutob
Publication year - 2022
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s357417
Subject(s) - medicine , radiological weapon , serology , pathology , radiology , immunology , antibody
Bone remodeling comprises balanced coupling of bone formation and resorption, and low bone mineral density (BMD) demonstrates high rates of bone resorption. Osteoporosis is a chronic asymptomatic disease with fragile bones and impending risk of fractures mediated by minor trauma. Whereas bone mineralization and integrity are determined by calcium and vitamin D, specific serum markers such as bone specific alkaline phosphatase (ALP) and osteocalcin (OC) play a vital role in bone formation.