Open AccessIdentifying of miRNA–mRNA Regulatory Networks Associated with Acute Kidney Injury by Weighted Gene Co-Expression Network Analysis
Author(s) -
Jie Xu,
Yunfei Xu
Publication year - 2022
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s353484
Subject(s) - acute kidney injury , microrna , kegg , gene , gene expression , bioinformatics , medicine , gene expression profiling , gene co expression network , renal function , gene regulatory network , biology , computational biology , genetics , transcriptome , gene ontology
Acute kidney injury (AKI) is a clinical emergency characterized by a dramatic decline in renal function and the accumulation of metabolic waste products in the body, with a high morbidity and mortality rate. The pathogenesis of AKI remains unclear and there are no effective treatment options.