Open AccessThe Mechanism and Prognostic Value of DNA Polymerase δ Subunits in Hepatocellular Carcinoma: Implications for Precision Therapy
Author(s) -
Qing Wang,
Song Zhang,
Qingdong Xu,
Jiahong Liang,
Peidong Zhang,
Wenlong Huang,
Zhiqiang Lin,
Shaodong Zheng,
Shen Gu,
Yan Jiang
Publication year - 2022
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s347162
Subject(s) - hepatocellular carcinoma , dna methylation , gene , medicine , cancer research , methylation , biology , cell cycle , genetics , gene expression
Polymerase δ (POLD) proteins is a pivotal B-family DNA polymerase in the process of genome replication and repair and are comprised of POLD1-4. The predictive value of POLDs in hepatocellular carcinoma (HCC) has not been evaluated until now.