Open AccessBioinformatic Analysis of Prognostic Value, Genetic Interaction, and Immune Infiltration of Chromobox Family Proteins in Breast Cancer
Author(s) -
Guochao Mao,
Yi Zheng,
Shuai Lin,
Li Ma,
Zhangjian Zhou,
Shuqun Zhang
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s343948
Subject(s) - medicine , breast cancer , immune system , infiltration (hvac) , value (mathematics) , computational biology , bioinformatics , oncology , cancer research , cancer , immunology , biology , machine learning , physics , computer science , thermodynamics
Breast cancer (BC) has become the malignant tumor with the highest incidence worldwide. As a critical components of epigenetic regulation complexes, chromobox (CBX) family members inhibit the transcription of target genes through chromatin modification, leading to the progression of various human diseases and cancers. So far, little is known about the role of different CBX members in BC, especially their association with immune cells.