Open AccessNonlinear Relationship Between AST-to-ALT Ratio and the Incidence of Type 2 Diabetes Mellitus: A Follow-Up Study
Author(s) -
Hua Niu,
Yinghua Zhou
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s341790
Subject(s) - hazard ratio , medicine , type 2 diabetes mellitus , confidence interval , incidence (geometry) , confounding , gastroenterology , rate ratio , retrospective cohort study , population , proportional hazards model , diabetes mellitus , endocrinology , mathematics , geometry , environmental health
The aspartate aminotransferase (AST) to alanine aminotransferase (ALT) ratio has been demonstrated to be associated with insulin resistance and metabolic syndrome. However, few studies have directly explored the association between the AST/ALT ratio and the incidence of type 2 diabetes mellitus (T2DM). As such, the present study aimed to investigate the relationship between the AST/ALT ratio and incident T2DM during follow-up in a population-based cohort.