Open AccessScreening of Some Indicators for Alpha-Thalassemia in Fujian Province of Southern China
Author(s) -
Lin Zheng,
Hailong Huang,
Xiaoqing Wu,
Linjuan Su,
Qingmei Shen,
Meiying Wang,
Na Lin,
Liangpu Xu
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s338419
Subject(s) - mean corpuscular volume , medicine , alpha thalassemia , thalassemia , genotype , hemoglobin a2 , mean corpuscular hemoglobin , beta thalassemia , hemoglobin , veterinary medicine , demography , biology , genetics , gene , sociology
Carrier screening is the most effective means of controlling the prevalence of alpha-thalassemia. However, due to the differences in ethnic populations and genotypes, the distribution of mean corpuscular volume (MCV), mean corpuscular hemoglobin (MCH) and hemoglobin A 2 (HbA 2 ) varies in different regions. This study aimed to examine screening efficiency of these indicators in different genotypes of alpha-thalassemia in Fujian Province, China.