Open AccessPrediction of Key Candidate Genes for Platinum Resistance in Ovarian Cancer
Author(s) -
Kaidi Guo,
Li Li
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s338044
Subject(s) - ovarian cancer , microarray , cisplatin , medicine , microarray analysis techniques , dna microarray , gene , cancer , bioinformatics , gene expression profiling , gene expression , cancer research , oncology , biology , genetics , chemotherapy
Ovarian cancer is one of the common malignant tumors of female reproductive organs, which seriously threatens the life and health of women. Resistance to chemotherapeutic drugs for ovarian cancer is the root cause of recurrence in most patients. The purpose of this study is to determine the differentially expressed genes of platinum resistance in ovarian cancer, and to screen out molecular targets and diagnostic markers that could be used to treat ovarian cancer platinum resistance.