Open AccessProgress in the Diagnosis and Treatment of COVID-19 in Children: A Review
Author(s) -
Libo Wang,
Li Gan,
Yuan Chen,
Yuelue Yang,
Gongxia Ling,
Jinyu Zheng,
Yiyang Zhou,
Tianlei Zhang,
Wei Lin,
Zhenlang Lin
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s335888
Subject(s) - medicine , asymptomatic , covid-19 , transmission (telecommunications) , epidemiology , disease , coronavirus , intensive care medicine , incubation period , population , pediatrics , virus , asymptomatic carrier , pandemic , immunology , infectious disease (medical specialty) , biochemistry , environmental health , incubation , electrical engineering , engineering , chemistry
Coronavirus disease 2019 (COVID-19) has been circulating in many countries around the world, characterized by long incubation period, strong infectivity, strong variability, high population susceptibility and diversified transmission methods. Its causative agent is severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Compared with adult patients, the clinical manifestations of COVID-19 in children are often dominated by mild or asymptomatic infections, but children are also important virus carriers and play an important role in the transmission of the virus. In addition, some children will show excessive inflammatory response and experience serious complications such as multisystem inflammatory syndrome in children (MIS-C). At present, the research on COVID-19 in children is still imperfect. This article will review epidemiological characteristics, the mechanism of action, variant characteristics, clinical manifestations, auxiliary examinations and treatment of children with COVID-19, in order to provide help for the diagnosis, treatment and research of children with COVID-19.