Open AccessNew Thresholds for AFP and Des-γ-Carboxy Prothrombin in Chronic Liver Disease Depending on the Use of Nucleoside Analogs and an Integrated Nomogram
Author(s) -
Tao Sun,
Ruicen Li,
Yiwen Qiu,
Shu Shen,
Wentao Wang
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s335400
Subject(s) - medicine , nomogram , gastroenterology , hepatocellular carcinoma , alpha fetoprotein , chronic hepatitis , logistic regression , prothrombin time , liver disease , nucleoside , stage (stratigraphy) , chronic liver disease , cirrhosis , virus , immunology , paleontology , stereochemistry , chemistry , biology
The thresholds of alpha-fetoprotein (AFP) and des-gamma-carboxy prothrombin (PIVKA-II) when detecting hepatocellular carcinoma (HCC) in chronic hepatitis B (CHB) patients with antiviral nucleoside analog (NA) remain controversial. A relevant integrated nomogram needs to be developed.