Open AccessConstruction and Integrated Analysis of Competitive Endogenous Long Non-Coding RNA Network in Thoracic Aortic Dissection
Author(s) -
Yingmei Shao,
Jun Luo,
Ye Liu,
Hao-Yu Ran,
Haoming Shi,
Cheng Zhang,
Qingchen Wu
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s335082
Subject(s) - medicine , aortic dissection , endogeny , coding (social sciences) , thoracic aortic aneurysm , bioinformatics , computational biology , cardiology , aortic aneurysm , aorta , biology , statistics , mathematics
Long non-coding RNAs (lncRNAs) can act as a competitive endogenous RNA (ceRNA) to regulate gene expression by sequestering the microRNA (miRNA). However, the lncRNA-miRNA-mRNA ceRNA network in thoracic aortic dissection (TAD) has been rarely documented.