Open AccessChanges in Bone Mineral Density Following Conventional Oral Phosphonate Treatment of Hypophosphatemic Osteomalacia: A Non-Randomized Controlled Study
Author(s) -
Yang Guo,
Yinghui Zhou,
Xian-Ping Wu,
Chengying Tang,
Min Wei,
Mo Zhang,
John Shepherd,
Bennett K. Ng,
Bo Fan,
Hong-Bo Zhou
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s332534
Subject(s) - medicine , osteomalacia , calcitriol , bone mineral , vitamin d and neurology , gastroenterology , hypophosphatemic rickets , hypophosphatemia , vitamin d deficiency , osteoporosis , urology , endocrinology , rickets
There are limited clinical studies aimed at solving the problem of the efficiency of conventional treatment with oral phosphate and calcitriol in adults with hypophosphatemic osteomalacia (HO). In addition, there still had no good non-hazardous markers to evaluate the severity of bone loss of osteomalacia before and after treatment. Therefore, the purpose of this study was to assess the efficacy of conventional treatment with a self-blended phosphate supplementation and calcitriol on patients with HO and whether bone mineral density (BMD) can be helpful for monitoring the efficacy.