Open AccessA Novel Autophagy-Related lncRNA Prognostic Signature Associated with Immune Microenvironment and Survival Outcomes of Gastric Cancer Patients
Author(s) -
Di Chen,
Mengmeng Wang,
Yushuang Xu,
Xin Jiang,
Lina Xiong,
Li Zhang,
Honglu Yu,
Zhifan Xiong
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s331959
Subject(s) - autophagy , tumor microenvironment , long non coding rna , medicine , proportional hazards model , immune system , cancer , oncology , survival analysis , microrna , receiver operating characteristic , competing endogenous rna , transcriptome , gene signature , cancer research , biology , gene , downregulation and upregulation , immunology , gene expression , apoptosis , genetics
Autophagy plays a crucial role in the initiation and progression of gastric cancer (GC). However, the role of autophagy-related lncRNAs in GC remains unknown. This study aimed to investigate the prognostic value of the autophagy-related lncRNA signature and its role in the tumor immune microenvironment (TIME) of GC.