
Mutational Analysis of Mitochondrial tRNA Genes in 200 Patients with Type 2 Diabetes Mellitus
Author(s) -
Liangyan Lin,
Dongdong Zhang,
Qingsong Jin,
Yaqin Teng,
Xiaoyan Yao,
Tiantian Zhao,
Xinmiao Xu,
Yongjun Jin
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s330973
Subject(s) - genetics , transfer rna , mitochondrial dna , gene , haplogroup , biology , pedigree chart , human mitochondrial genetics , sanger sequencing , mutation , allele , haplotype , rna
Previous studies showed that variants in mitochondrial DNA (mtDNA) are associated with type 2 diabetes mellitus (T2DM). However, the relationships between mitochondrial tRNA (mt-tRNA) variants and T2DM remain poorly understood.