Open AccessEvaluation of Ferroptosis-related Gene AKR1C1 as a Novel Biomarker Associated with the Immune Microenvironment and Prognosis in Breast Cancer
Author(s) -
Zeyu Zhang,
Xiangyuan Qiu,
Yuanliang Yan,
Qiujiu Liang,
Yuan Cai,
Bi Peng,
Zhijie Xu,
Fada Xia
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s329031
Subject(s) - immune system , transcriptome , carcinogenesis , cancer research , breast cancer , medicine , tumor microenvironment , chemokine , cancer , immunology , biomarker , gene , biology , gene expression , genetics
Ferroptosis is the latest-discovered, iron-dependent form of regulated cell death. It has been increasingly recognized that ferroptosis-related genes participate in oncogenesis and development of cancers, including breast cancer ( BRCA ). Thus, It is important to explore the biofunctions of ferroptosis-related genes in BRCA .