Open AccessInfluence of GSTP-1 Polymorphism on the Prognosis of Patients with High-Grade Glioma Who Received Temozolomide Plus Radiotherapy Adjuvant Treatment
Author(s) -
Debao Zhi,
Zhiyu Wang,
Tong Xie,
Wen-Wen Tu
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s328810
Subject(s) - temozolomide , medicine , glioma , regimen , genotyping , radiation therapy , gastroenterology , genotype , adjuvant , oncology , surgery , gene , cancer research , biology , biochemistry
Glutathione S-Transferase P 1 (GSTP-1) gene plays an important physiological role in the body. The present study was conducted to identify the clinical implication of GSTP-1 gene polymorphism on the prognosis of patients with high-grade glioma (HGG) who received temozolomide plus radiotherapy adjuvant treatment.