Open AccessEfficacy of a Nasal Spray Containing Iota-Carrageenan in the Postexposure Prophylaxis of COVID-19 in Hospital Personnel Dedicated to Patients Care with COVID-19 Disease
Author(s) -
Juan Manuel Figueroa,
Mónica E. Lombardo,
Ariel Dogliotti,
Luis Pedro Flynn,
Robert P. Giugliano,
Guido Simonelli,
Ricardo Valentini,
A. Velasco Ramos,
Pablo Romano,
Marcelo Marcote,
Alicia Michelini,
Alejandro Salvado,
Emilio Sykora,
Cecilia Kniz,
Marcelo Kobelinsky,
David Manuel Salzberg,
Diana Jerusalinsky,
Osvaldo D. Uchitel
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s328486
Subject(s) - medicine , placebo , nasal spray , covid-19 , clinical trial , incidence (geometry) , randomized controlled trial , nasal administration , disease , immunology , pathology , infectious disease (medical specialty) , physics , alternative medicine , optics
Iota-Carrageenan (I-C) is a sulfate polysaccharide synthesized by red algae, with demonstrated antiviral activity and clinical efficacy as nasal spray in the treatment of common cold. In vitro, I-C inhibits SARS-CoV-2 infection in cell culture.