Open AccessELTD1 Promotes Gastric Cancer Cell Proliferation, Invasion and Epithelial–Mesenchymal Transition Through MAPK/ERK Signaling by Regulating CSK
Author(s) -
Bo Sun,
Fang-Jing Zhong
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s325495
Subject(s) - mapk/erk pathway , cancer research , epithelial–mesenchymal transition , metastasis , oncogene , gene knockdown , cell growth , medicine , cancer , in vivo , signal transduction , biology , microbiology and biotechnology , cell culture , cell cycle , biochemistry , genetics
Patients with gastric cancer (GC) often die from metastasis. However, the exact molecular mechanism underlying GC metastasis is complicated and still remains elusive. Epidermal growth factor, latrophilin and seven-transmembrane domain-containing 1 (ELTD1), has been reported to be involved in cancer metastasis, but its role in GC is still missing.