Open AccessFour Immune-Related Genes (FN1, UGCG, CHPF2 and THBS2) as Potential Diagnostic and Prognostic Biomarkers for Carbon Nanotube-Induced Mesothelioma
Author(s) -
Dongli Xie,
Jianchen Hu,
Tong Wu,
Kangli Cao,
Xiaogang Luo
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s324365
Subject(s) - gene , computational biology , microarray , medicine , microarray analysis techniques , disease , immune system , bioinformatics , biology , gene expression , oncology , immunology , genetics
Malignant pleural mesothelioma (MPM), a highly aggressive cancer, was mainly attributed to asbestos exposure. Carbon nanotubes (CNTs) share similar negative features to asbestos, provoking concerns about their contribution to MPM. This study was used to identify genes associated with CNT-induced MPM.