Open AccessIs Prenatal Diagnosis Necessary for Fetal Isolated Nasal Bone Absence or Hypoplasia?
Author(s) -
Feng Zhang,
Wei Long,
Qin Zhou,
Jing Wang,
Ye Shi,
Jianbing Li,
Qiuwei Wang
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s322359
Subject(s) - medicine , nasal bone , hypoplasia , abnormality , exome sequencing , prenatal diagnosis , dysplasia , fetus , trisomy , genetic counseling , gene duplication , pediatrics , obstetrics , pregnancy , bioinformatics , pathology , surgery , genetics , mutation , biology , gene , psychiatry
This study aimed to explore the value of chromosomal microarray analysis (CMA) and whole exome sequencing (WES) in the prenatal diagnosis of fetal isolated nasal bone absence (INBA) or isolated nasal bone hypoplasia (INBH). We hope to provide additional relevant information for clinical counseling.