Open AccessKRT7 Overexpression is Associated with Poor Prognosis and Immune Cell Infiltration in Patients with Pancreatic Adenocarcinoma
Author(s) -
Yuexian Li,
Shanshan Zhou,
Biwei Wei,
Zhihai Liang
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s313584
Subject(s) - immune system , medicine , adenocarcinoma , cancer research , gene expression profiling , human protein atlas , pancreatic cancer , gene , gene expression , biology , cancer , immunology , protein expression , genetics
Pancreatic adenocarcinoma (PAAD) is a deadly tumor with a high recurrence rate and poor prognosis. Keratin 7 (KRT7) is a member of the keratin gene family that is involved in the regulation of cell growth, migration and apoptosis in many cancers. However, the role of KRT7 and its biological functions in PAAD remain unclear. We systemically analyzed the expression and clinical values of KRT7 in PAAD.