Open AccessKDELC1 and TRMT1 Serve as Prognosis-Related SARS-CoV-2 Proteins Binding Human mRNAs and Promising Biomarkers in Clear Cell Renal Cell Carcinoma
Author(s) -
Can-Xuan Li,
Yuzhi Yao,
Dan Long,
Xiaobin Lin
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s312416
Subject(s) - clear cell renal cell carcinoma , human protein atlas , downregulation and upregulation , renal cell carcinoma , proportional hazards model , medicine , survival analysis , clear cell , cancer research , cancer , biology , oncology , computational biology , gene , protein expression , genetics
SARS-CoV-2 proteins binding human mRNAs (SPBRs) have been proven to regulate a variety of tumor-related functions in different types of cancer. However, their biological roles and potential mechanisms in clear cell renal cell carcinoma (ccRCC) are still elusive. Herein, we investigate the expression and prognostic value of SPBRs in ccRCC through bioinformatics methods.