Open AccessHematopoietic Stem-Cell Transplantation versus Immunosuppressive Therapy in Patients with Adult Acquired Severe Aplastic Anemia: A Cost-Effectiveness Analysis
Author(s) -
Mengxue Zhang,
Qian Wang,
Xiaoqin Wang
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s310844
Subject(s) - medicine , hematopoietic stem cell transplantation , aplastic anemia , transplantation , quality adjusted life year , cost effectiveness , pediatrics , anemia , bone marrow , risk analysis (engineering)
Controversy remains regarding which therapy to initially select for severe aplastic anemia (SAA) patients aged 35-50. This cost-effectiveness analysis aimed to use the Markov model to compare immunosuppressive therapy (IST) with hematopoietic stem-cell transplantation (HSCT) in age-stratified patients with SAA.