Open AccessCorrelation Between Level of Interleukin-37 and Rheumatoid Arthritis Progression
Author(s) -
Jifeng Zhu,
Changzhan Xie,
Hongjiu Qiu,
Ling Shi
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s309436
Subject(s) - medicine , rheumatoid arthritis , peripheral blood mononuclear cell , immunology , inflammation , immune system , receiver operating characteristic , synovial fluid , cytokine , interleukin , population , arthritis , interleukin 18 , interleukin 6 , pathology , osteoarthritis , biology , biochemistry , alternative medicine , environmental health , in vitro
Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory disease that primarily affects joints. Interleukin-37 (IL-37) is an anti-inflammatory cytokine that is known to suppress immune response and inflammation. The objective of this study is to evaluate the correlation between level of IL-37 and RA progression using the disease activity score in 28 joints (DAS-28).