Open AccessThe Lymphocyte Depletion in Patients with Acute Ischemic Stroke Associated with Poor Neurologic Outcome
Author(s) -
Cep Juli,
Henhen Heryaman,
Arnengsih Nazir,
Eng-Tat Ang,
Irma Ruslina Defi,
Uni Gamayani,
Nur Atik
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s308325
Subject(s) - medicine , stroke (engine) , lymphocyte , ischemic stroke , acute stroke , intensive care medicine , bioinformatics , immunology , ischemia , mechanical engineering , tissue plasminogen activator , engineering , biology
Inflammation plays an important role and is involved in all stages of acute ischemic stroke. One of these stages involves the recruitment of leukocytes from the peripheral circulation into the ischemic tissue. Lymphocytes as a subtype of leukocytes are important mediators and can become a predictor of neurological outcome. Several studies have been conducted regarding the correlation between differential lymphocyte counts and acute ischemic stroke. Most of these studies analyzed lymphocyte ratio to other leukocyte subtypes such as neutrophils and monocytes. This study specifically observed the role of lymphocytes as an indicator of the inflammatory response in patients with acute ischemic stroke. This study aimed to observe the correlation among risk factors, infarct location, leukocyte counts, lymphocyte value and neurologic output in acute ischemic stroke patients.