Open AccessCirculating Osteoprotegerin in Chronic Kidney Disease and All-Cause Mortality
Author(s) -
Joanna Kamińska,
Marek Stopiński,
Krzysztof Mucha,
Michał Pac,
Marek Gołębiowski,
Monika A. Niewczas,
Leszek Pączek,
Bartosz Foroncewicz
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s302251
Subject(s) - osteoprotegerin , medicine , osteopontin , kidney disease , fibroblast growth factor 23 , osteocalcin , bone remodeling , end stage renal disease , disease , endocrinology , gastroenterology , calcium , parathyroid hormone , alkaline phosphatase , biochemistry , chemistry , receptor , enzyme , activator (genetics)
Chronic kidney disease (CKD) is associated with cardiovascular disease (CKD), mineral and bone disorder (CKD-MBD) and high mortality. Bone-related factors such as osteopontin (OPN), osteocalcin (OC), osteoprotegerin (OPG) and fibroblast growth factor 23 (FGF23) were linked to cardiovascular complications of CKD and are expected to have predictive value in CKD patients.