Open AccessWhole-Exome Sequencing for Identifying Genetic Causes of Intellectual Developmental Disorders
Author(s) -
Yuxiong Guo,
Hong-Xia Ma,
Yuxin Zhang,
Zhihong Chen,
Qixiao Zhai
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s300775
Subject(s) - pachygyria , atrx , medicine , proband , ventriculomegaly , corpus callosum , wechsler intelligence scale for children , exome sequencing , intellectual disability , microcephaly , autism , genetics , wechsler adult intelligence scale , pediatrics , psychiatry , lissencephaly , gene , pathology , cognition , biology , pregnancy , mutation , fetus
Intellectual developmental disorders (IDD) generally refers to the persistent impairment of cognitive activities and mental retardation caused by physical damage to the brain or incomplete brain development. We aimed to explore its genetic causes.