Open AccessEvolving Treatment Patterns for Hospitalized COVID-19 Patients in the United States in April 2020–July 2020
Author(s) -
Xiaozhou Fan,
Barbara H. Johnson,
Stephen S. Johnston,
N. Elangovanraaj,
Paul Coplan,
Rahul Khanna
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s290118
Subject(s) - medicine , hydroxychloroquine , gee , azithromycin , covid-19 , pandemic , population , generalized estimating equation , emergency medicine , pediatrics , demography , disease , virology , outbreak , statistics , environmental health , mathematics , sociology , infectious disease (medical specialty) , microbiology and biotechnology , biology , antibiotics
We sought to examine the trend (April-July) in the treatment patterns among hospitalized COVID-19 patients using the Premier Healthcare Database (PHD). In the analysis, we identified 53,264 patients from 302 hospitalsthat continuously provided inpatient data from April 1, 2020 to July 31, 2020 to the PHD, a nationwide, population-based multihospital research database in the US. We used generalized estimating equations (GEE) models to assess changes in the proportion of therapies used during the study period. After adjusting for patient and provider factors, a decline in hydroxychloroquine and an increase in azithromycin and dexamethasone were observed among COVID-19 patients during the 4-month study period.