Open Access<p>Anaplastic Pleomorphic Xanthoastrocytoma: A Case Report and Literature Review</p>
Author(s) -
Jing Liu,
Yihong Sun,
Xia Liu
Publication year - 2020
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s285989
Subject(s) - pleomorphic xanthoastrocytoma , pathology , glial fibrillary acidic protein , olig2 , vimentin , medicine , synaptophysin , anaplastic astrocytoma , idh1 , astrocytoma , oligodendrocyte , glioma , immunohistochemistry , biology , cancer research , myelin , mutation , central nervous system , gene , biochemistry
With an incidence of less than 1% among astrocytomas, pleomorphic xanthoastrocytoma (PXA) is rare. When its mitotic activity exceeds 5 mitoses/10 high-power fields, PXA is defined as anaplastic pleomorphic xanthoastrocytoma (APXA). This report documents the clinical manifestations and histopathological characteristics of APXA to help prevent future misdiagnoses.