Open AccessLong Non-Coding RNA HCG11 Aggravates Osteosarcoma Carcinogenesis via Regulating the microRNA-579/MMP13 Axis
Author(s) -
Lili Wang,
Jingzhen Zhou,
Yong Zhang,
Tao Hu,
Yongning Sun
Publication year - 2020
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s274641
Subject(s) - microrna , carcinogenesis , long non coding rna , downregulation and upregulation , competing endogenous rna , cancer research , western blot , osteosarcoma , cell growth , medicine , biology , gene , genetics
Previous studies have suggested that long non-coding RNAs (lncRNAs) were involved in tumorigenesis of various human carcinomas, including osteosarcoma (OS). However, the expression and specific role of lncRNA HLA complex group 11 (HCG11) in OS remain unknown. The current study aimed at revealing the role of lncRNA HCG11 and its related mechanism in OS.