Open AccessRelationship of Histopathological Representation of Excessive Proliferation of Trophoblast Cells with the Possibility of Malignant Events After Complete Hydatidiform Mole
Author(s) -
Maringan Diapari Lumban Tobing,
Futiha Arabia,
Yudi Mulyana Hidayat,
Kemala Isnainiasih Mantilidewi
Publication year - 2021
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s271635
Subject(s) - malignancy , medicine , mole , choriocarcinoma , gynecology , trophoblast , trophoblastic neoplasm , pathology , pregnancy , biology , fetus , gestation , placenta , genetics
Fifteen to twenty percent of the patients with complete hydatidiform mole transform malignancy into gestational trophoblastic tumors. The marked proliferation of trophoblastic cells is one of the characteristics that determines high risk for the occurrence of post-hydatidiform mole malignancy. The objective of the study was to analyze the histopathologic feature of the marked proliferation of trophoblastic cells as a role in post-hydatidiform mole malignancy that can be used as a determinant of the risk of malignancy post-hydatidiform mole.