Open Access<p>Deficient Expression of <em>DGCR8</em> in Human Testis is Related to Spermatogenesis Dysfunction, Especially in Meiosis I</p>
Author(s) -
Emad Babakhanzadeh,
Majid Nazari,
Masoud Dehghan Tezerjani,
Shiva Aghaei,
Sina Ghasemifar,
Mehdi Hosseinnia,
Mahta Mazaheri
Publication year - 2020
Publication title -
international journal of general medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.722
H-Index - 36
ISSN - 1178-7074
DOI - 10.2147/ijgm.s255431
Subject(s) - azoospermia , spermatogenesis , andrology , medicine , western blot , gene expression , male infertility , gene , sertoli cell , sperm , biology , infertility , genetics , pregnancy
DiGeorge syndrome critical region gene 8 ( DGCR8 ) contributes to miRNA biogenesis, and defects in its expression could lead to defects in spermatogenesis.