Open AccessBloodstream Infections in Patients with Rectal Colonization by Carbapenem-Resistant Enterobacteriaceae: A Prospective Cohort Study
Author(s) -
Wenwen Chu,
Xiubing Hang,
Xin Li,
Naifang Ye,
Wei Tang,
Yafei Zhang,
Xiyao Yang,
Min Yang,
Yansheng Wang,
Zhou Liu,
Qiang Zhou
Publication year - 2022
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s383688
Subject(s) - carbapenem resistant enterobacteriaceae , multilocus sequence typing , microbiology and biotechnology , klebsiella pneumoniae , biology , medicine , genotype , escherichia coli , gene , biochemistry
Carbapenem-resistant Enterobacteriaceae (CRE) infection has become a concerning threat, especially in hospital settings; however, its phenotypic characterization, association with rectal colonization and subsequent bloodstream infections (BSI) remain to be clarified. This study aimed to investigate the incidence and risk factors of CRE infection in rectal CRE carriers and to understand the clonality of carbapenem-resistant Klebsiella pneumoniae (CRKP) strains and their association with subsequent BSI in these patients.