Open AccessMortality Risk Factors and Prognostic Analysis of Patients with Multi-Drug Resistant Enterobacterales Infection
Author(s) -
Xinchun Wang,
Qi Li,
Jianbang Kang,
Donghong Yin,
Xiaoxia Li,
Shuyun Wang,
Qian Guo,
Yan Song,
Jing Wang,
Jinju Duan
Publication year - 2022
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s366808
Subject(s) - enterobacter cloacae , klebsiella pneumoniae , drug resistance , medicine , cephalosporin , multiple drug resistance , microbiology and biotechnology , escherichia coli , antibiotics , biology , gene , biochemistry
The data from the China Network Antibacterial Surveillance Center (http://www.chinets.com) showed that the prevalence of Escherichia coli ( E. coli ), Klebsiella pneumoniae (KP), and Enterobacter cloacae (ecl), was 18.96%, 14.12%, and 2.74% in 2022, respectively. The resistance rates of E. coli and KP to 3rd or 4th generation cephalosporins were 51.7% and 22.1%, to carbapenems was 1.7% and 3.9%, to quinolones was 55.9% in Shanxi. The generation of extended-spectrum beta-lactamases (ESBLs) is a major mechanism resulting in drug resistance in Enterobacterales . To determine the mortality risk factors of multi-drug resistant Enterobacterales (MDRE) and multi-drug resistant Klebsiella pneumoniae (MDR-KP) infection.