Open Access
NWMN2330 May Be Associated with the Virulence of Staphylococcus aureus by Increasing the Expression of hla and saeRS
Author(s) -
Li Liu,
Bingjie Wang,
Jingyi Yu,
Yinjuan Guo,
Fangyou Yu
Publication year - 2022
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s365314
Subject(s) - virulence , staphylococcus aureus , microbiology and biotechnology , biology , mutant , staphylococcal infections , pathogen , sepsis , gene , virology , bacteria , immunology , genetics
Staphylococcus aureus is an opportunistic pathogen that can cause life-threatening bloodstream infections such as sepsis and endocarditis. In recent years, the emergence and increase of methicillin-resistant and multidrug-resistant S. aureus has posed a great challenge to the antibiotic treatment of infectious diseases. Anti-virulence strategies targeting virulence factors are an effective new therapy for the treatment of S. aureus infections.