Open AccessMALDI-TOF MS-Based Clustering and Antifungal Susceptibility Tests of Talaromyces marneffei Isolates from Fujian and Guangxi (China)
Author(s) -
Lili Fang,
Minxue Liu,
Chen Huang,
Xiaoxuan Ma,
Yanqing Zheng,
Wenjuan Wu,
Jingjie Guo,
Jiangshan Huang,
Huanji Xu
Publication year - 2022
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s364439
Subject(s) - voriconazole , posaconazole , anidulafungin , itraconazole , penicillium marneffei , microbiology and biotechnology , micafungin , amphotericin b , fluconazole , biology , antifungal , virology , human immunodeficiency virus (hiv) , coinfection
Talaromyces marneffei is a life-threatening pathogen that causes systemic talaromycosis in immunocompromised and acquired immunodeficiency syndrome (AIDS) patients. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) as a tool to cluster T. marneffei isolates is rarely reported and the data on antifungal susceptibility of T. marneffei isolated in the southern region of China, especially in Fujian, is hardly found.