Open AccessEmergence of a Multidrug-Resistant Escherichia coli Co-Carrying a New mcr-1.33 Variant and blaNDM-5 Genes Recovered from a Urinary Tract Infection
Author(s) -
Danni Bao,
Xiaohong Xu,
Yizhang Wang,
Fengjiao Zhu
Publication year - 2022
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s358566
Subject(s) - biology , plasmid , escherichia coli , microbiology and biotechnology , multilocus sequence typing , broth microdilution , whole genome sequencing , cefoxitin , antibiotic resistance , genome , genetics , gene , antimicrobial , antibiotics , bacteria , minimum inhibitory concentration , genotype , staphylococcus aureus
Carbapenem-resistant Enterobacterales (CRE) are a significant threat to worldwide public health, resulting in increased morbidity, death, hospitalization time and healthcare expenses. Here, the genomic and phylogenetic characteristics of a multidrug-resistant Escherichia coli isolate carrying both the new mcr-1.33 variant and bla NDM-5 gene obtained from a urinary tract infection in China are investigated.