Open AccessGenetic Diversity and in vitro Activity of Aztreonam/Avibactam and Ceftazidime/Avibactam Against Carbapenem-Resistant Enterobacterales: A Multi-Center Study in Southwest China
Author(s) -
Shan Sun,
Kai Chen,
Xiangpeng Kong,
Wenjun Tian,
Siqiang Niu
Publication year - 2022
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s357396
Subject(s) - enterobacter cloacae , avibactam , klebsiella pneumoniae , ceftazidime/avibactam , aztreonam , microbiology and biotechnology , broth microdilution , biology , carbapenem , colistin , ceftazidime , carbapenem resistant enterobacteriaceae , amikacin , escherichia coli , imipenem , antimicrobial , minimum inhibitory concentration , antibiotic resistance , gene , antibiotics , bacteria , genetics , pseudomonas aeruginosa
This study aimed to understand the distribution characteristics of carbapenemase genes and assess the antimicrobial activities of aztreonam/avibactam (ATM/AVI) and ceftazidime/avibactam (CAZ/AVI) against carbapenem-resistant Enterobacterales (CRE) isolates in Chongqing, Southwest China.