Open AccessCCL25 Inhibition Alleviates Sepsis-Induced Acute Lung Injury and Inflammation
Author(s) -
Demeng Xia,
Sheng Wang,
Anwei Liu,
Lei Li,
Panyu Zhou,
Shuogui Xu
Publication year - 2022
Publication title -
infection and drug resistance
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s352544
Subject(s) - ccl25 , chemokine , in vivo , inflammation , sepsis , immunology , lipopolysaccharide , cancer research , in vitro , medicine , biology , chemokine receptor , biochemistry , microbiology and biotechnology
Acute lung injury (ALI) is a common clinical syndrome with high mortality. The chemokine ligand 25 (CCL25) is involved in inflammation, leukocyte trafficking and immunoregulation. However, the role and mechanism of CCL25 in ALI are not fully understood yet. The aim of this study was to explore the relationship between acute lung injury and CCL25.