Open AccessTalaromyces Marneffei Infection in Lung Cancer Patients with Positive AIGAs: A Rare Case Report
Author(s) -
Fanhai Lin,
Zhenming Yang,
Ye Qiu,
Wen Zeng,
Guangnan Liu,
Jianquan Zhang
Publication year - 2021
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s340694
Subject(s) - medicine , lung cancer , lung , penicillium marneffei , immunodeficiency , cancer , immunology , opportunistic infection , human immunodeficiency virus (hiv) , pathology , viral disease , immune system , coinfection
Talaromyces marneffei is considered to commonly cause infection in individuals with human immunodeficiency virus (HIV) infection. However, the epidemiology of T. marneffei has changed, and an increasing number of HIV-negative but immunodeficient patients are infected with T. marneffei . The mechanisms of T. marneffei infection of HIV-negative hosts are complex and diverse. We report 2 cases of HIV-negative lung cancer with T. marneffei infection and positive anti-interferon-gamma autoantibodies (AIGAs) to provide clinical experience.