Open AccessThe Potential of Digital Polymerase Chain Reaction for Improving Diagnostic Yield of Nontuberculous Mycobacteria Pulmonary Disease
Author(s) -
Yoichi Nishii,
Kazuki Furuhashi,
Saki Nakamura,
Masayuki Nishio,
Yuki Nakamura,
Kengo Ushiro,
Kentaro Ito,
Tadashi Sakaguchi,
Yuta Suzuki,
Kentaro Fujiwara,
Taro Yasuma,
Tetsu Kobayashi,
Cori. D’Alessandro-Gabazza,
Esteban C. Gabazza,
Osamu Taguchi,
Osamu Hataji
Publication year - 2021
Publication title -
infection and drug resistance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.033
H-Index - 39
ISSN - 1178-6973
DOI - 10.2147/idr.s338165
Subject(s) - nontuberculous mycobacteria , polymerase chain reaction , digital polymerase chain reaction , pulmonary disease , yield (engineering) , medicine , microbiology and biotechnology , mycobacterium , biology , pathology , genetics , tuberculosis , physics , gene , thermodynamics
Many patients with nontuberculous mycobacteria pulmonary disease are asymptomatic. The disease diagnosis is confirmed in only a small proportion of patients with radiological findings suspicious for nontuberculous mycobacteria pulmonary disease. Thus, many patients remained undiagnosed. Here, we evaluated the diagnostic value of digital polymerase chain reaction (PCR) in nontuberculous mycobacteria pulmonary disease.